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Publications
21. Access to Synthetic Fold-switching Proteins Using Automated Flow Chemistry
Kjerfve, C.;Kwao, J.K.; Glover, J.; Wood, B.; Golden, C.; Truex, N.L.
PREPRINT: ChemRxiv. 2025. html.
20. An artificial transcription factor that activates potent interferon-γ expression in human Jurkat T Cells
King, A.; Noblitt, D.; Sherron, O.; Kjerfve, C.; Pless, L.; and Truex, N.L.
Front. Mol. Med. 2025, 4, 1492370. html pdf si fastq.
19. Protective antigen-mediated delivery of an anti-CRISPR protein for precision genome editing
Vera, A.O.; Truex, N.L.; Sreekanth, V.; Pentelute, B.L. Choudhary, A.; Raines, R.T.
PREPRINT: BioRxiv, 2025. html pdf
18. Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons
Truex, N.L.; Mohapatra, S.; Melo, M.; Rodriguez, J.; Li, N.; Abraham, W.; Sementa, D.; Touti, F.; Keskin, D.B.; Wu, C.J.;Irvine, D.J.;Gómez-Bombarelli, R.; Pentelute, B.L.
ACS Cent. Sci. 2024, 10, 793–802. html pdf si. PREPRINT: BioRxiv, 2023. html pdf
17. β-Hairpin Alignment Alters Oligomer Formation in Aβ-Derived Peptides
Ruttenberg, S. M.; Kreutzer, A. G.; Truex, N. L.; Nowick, J. S.
Biochemistry 2024, 63, 212–218. html pdf si
16. Enhanced Vaccine Immunogenicity Enabled by Targeted Cytosolic Delivery of Tumor Antigens into Dendritic Cells
Truex, N.L., Rondon, A.; Rössler, S.L.; Hanna, C.C.; Cho, Y.; Wang, B.-Y.; Backlund, C.M.; Lutz, E.A.; Irvine, D.J.; Pentelute, B.L.
ACS Cent. Sci. 2023, 9, 1835–1845. html pdf si
15. Palladium−Peptide Oxidative Addition Complexes for Bioconjugation
Rojas, A.J.; Wolfe, J.M.; Dhanjee, H.H.; Buslov, I.; Truex, N.L., Liu, R.Y.; Massefski, W.W.; Pentelute, B.L.; Buchwald, S.L.
Chem. Sci. 2022, 13, 11891–11895. html pdf si
14. Palladium-Mediated Incorporation of Carborane into Small Molecules, Peptides, and Proteins
Gazvoda, M.; Dhanjee, H.H.; Rodriguez, J.; Brown, J.S.; Farquhar, C.F.; Truex, N.L.; Loas, A.; Buchwald, S.L.; Pentelute, B.L.
J. Am. Chem. Soc. 2022, 144, 7852–7860. html pdf si
13. IgG-Engineered Protective Antigen for Cytosolic Delivery of Proteins into Cancer Cells
Lu, Z.; Truex, N.L.; Melo, M.B.; Cheng, Y.; Li, N.; Irvine, D.J.; Pentelute, B.L.
ACS Cent. Sci. 2021, 7, 365–378. html pdf si
12. Anthrax Protective Antigen Retargeted with Single-Chain Variable Fragments Delivers Enzymes to Pancreatic Cancer Cells
Loftis, A.R.; Santos, M.S.; Truex, N.L.; Biancucci, M.; Satchell, K.J.F.; Pentelute, B.L.
ChemBioChem. 2020, 21, 2772–2776. html pdf si
11. Targeting Cancer Gene Dependencies with Anthrax-Mediated Delivery of Peptide Nucleic Acids
Lu, Z.Y.; Paolella, B.R.; Truex, N.L.; Loftis, A.R.; Liao, X.L.; Rabideau, A.E.; Brown, M.; Busanovich, J.; Beroukhim, R.; Pentelute, B.L.
ACS Chem. Biol. 2020, 15, 1358–1369. html pdf si
10. A Novel, Safe, Fast and Efficient Treatment for Her2-Positive and Negative Bladder Cancer Utilizing an EGF-Anthrax Toxin Chimera
Jack, S.; Madhivanan, K.; Ramadesikan, S.; Subramanian, S.; Edwards,D.; Elzey,B.; Dhawan, D.; McCluskey, A.; Kischuk, E.; Loftis, A.R.; Truex, N.L.; Santos, M.; Lu, Z.; Rabideau, A.; Pentelute, B.L.; Collier, R.J.; Kaimakliotis, H.; Koch, M.; Ratliff, T.; Knapp, D.; Aguilar, R.C.
Int. J. Cancer. 2020, 146, 449–460. html pdf si
9. Automated Flow Synthesis of Tumor Neoantigen Peptides for Personalized Immunotherapy
Truex, N.L.; Holden, R.L.; Wang, B.Y.; Chen, P.G.; Hanna, S.; Hu, Z.T.; Shetty, K.; Olive, O.; Neuberg, D.; Hacohen, N.; Keskin, D.B.;
Ott, P.A.; Wu, C.J.; Pentelute, B.L.
Sci. Rep. 2020, 10, 723. html pdf si
8. Effects of N-Terminal Residues on the Assembly of Constrained β-Hairpin Peptides Derived from Aβ
Samdin, T.D.; Wierzbicki, M.; Kreutzer, A.G.; Howitz, W.J.; Valenzuela, M.; Smith, A.; Sahrai, V.; Truex, N.L.; Klun, M.; Nowick, J.S.
J. Am. Chem. Soc. 2020, 142, 11593–11601. html pdf si
7. Effects of Charge and Hydrophobicity on the Oligomerization of a Peptide Derived from IAPP
Wang, Y.; Truex, N.L.; Vo, N. D. P.; Nowick, J.S.
Bioorganic Med. Chem. 2018, 26, 1151–1156. html pdf
6. Transmembrane Proteins: Amyloids Hidden in Plain Sight?
Truex, N.L.; Nowick, J.S.
Biochemistry, 2017, 56, 4735–4736. html pdf
5. A Tetramer Derived from Islet Amyloid Polypeptide
Wang, Y.; Kreutzer, A.G.; Truex, N.L.; Nowick, J.S.
J. Org. Chem. 2017, 82, 7905–7912. html pdf si
4. Assembly of Peptides Derived from β-Sheet Regions of β-Amyloid
Truex, N.L.; Wang, Y.; Nowick, J.S.
J. Am. Chem. Soc. 2016, 138, 13882–13890. html pdf si
3. Coassembly of Peptides Derived from β-Sheet Regions of β-Amyloid
Truex, N.L.; Nowick, J.S.
J. Am. Chem. Soc. 2016, 138, 13891–13900. html pdf si
2. Square Channels formed by a peptide derived from transthyretin
Yoo, S.; Kreutzer, A.G.; Truex, N.L.; Nowick, J.S.
Chem. Sci. 2016, 7, 6946–6951. html pdf si
1. Pd-Catalyzed Cross-Coupling Reactions Exhibiting Catalyst Turnover Numbers Exceeding One Million
Xu, S.; Truex, N.L.; Swathi, M.; Negishi, E.-I.
Arkivoc 2012, 7, 242. (Dedicated in Honor of Prof. Keith Smith). html pdf
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